PEP Oral Medication

An updated review of the tolerability and completion rates of various ARV regimens for HIV post-exposure prophylaxis supports the use of DTG together with TDF + 3TC (or FTC) for HIV post-exposure prophylaxis, as 90% of individuals receiving this regimen complete post-exposure prophylaxis. Regimen selection Preferred regimen Tenofovir 300 mg / Lamivudine 300 mg / Dolutegravir 50 mg once a day x 4 weeks  as a fixed-dose combination TLD should be considered as the gold standard and should be readily available . Alternatives should only be be considered in exceptional circumstances if TLD is not suitable or not tolerated.